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Article

Exploring novel drug targets for atopic dermatitis through plasma proteome with genome.

Archives of dermatological research - 13 Aug 2024

Wu Wenhua, Su Hao, Chen Zhengrui, Wei Shanshan

Abstract excerpt

Atopic dermatitis (AD) is a chronic inflammatory disease with a complex and heterogeneous clinical presentation, leading to treatment limitations. Therefore, there is an urgent demand for new therapeutic drug targets. This study utilized Summary-data-based Mendelian randomization (SMR) to identify potential drug targets for AD. Summary statistics for 2,940 human plasma proteins were obtained from the UK Biobank,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39136778
DOI: 10.1007/s00403-024-03262-z

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