Article

Discovery of α-Glucosidase Inhibitors from Paenibacillus sp. JNUCC 31 via Genome Mining, Metabolite Profiling, and In Silico Analysis

2025-07-21

Abstract excerpt

<title>Abstract</title> <p>The increasing prevalence of type 2 diabetes has driven an increasing demand for safe and effective α-glucosidase inhibitors (AGIs). Paenibacillus spp., known producers of diverse secondary metabolites, remain underexplored as AGI sources. This study aims to evaluate the biosynthetic potential and α-glucosidase inhibitory activity of Paenibacillus sp. JNUCC 31. Genomic annotation of the...

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Literature Corpus work: 59565006-0404-5f3f-91e3-d744469a0b59
DOI: 10.21203/rs.3.rs-7011231/v1

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