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Tandem mass spectral metabolic profiling of 54 actinobacterial strains and their 459 mutants.

Scientific data - 7 Sept 2024

Tay Dillon W P, Tan Lee Ling, Heng Elena, Zulkarnain Nadiah, Chin Elaine Jinfeng, Tan Zann Yi Qi, Leong Chung Yan, Ng Veronica Wee Pin, Yang Lay Kien, Seow Deborah C S, Kanagasundaram Yoganathan, Ng Siew Bee, Lim Yee Hwee, Wong Fong Tian

Abstract excerpt

Natural products encompass a diverse range of compounds with high impact applications in consumer care, agriculture and most notably, therapeutics. However, despite the expansive chemical repertoire indicated in genomic information of microbes, only a small subset can be obtained under laboratory conditions. To increase accessible chemical space and realize Nature's full chemical potential, a multi-pronged...

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PMID: 39244610
DOI: 10.1038/s41597-024-03833-9
PMCID: PMC11380661

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