Article

Re-analysis of Transcriptomic and Proteomic Data Using Multi-Omics Approaches Identifies Biomarkers of Diabetes-Associated Complications in an INS Mutant Pig Model

2026-03-07

Abstract excerpt

Mutant Insulin Induced Diabetes of Youth (MIDY) is an established porcine model caused by the INSC94Y mutation, which results in misfolded insulin, leading to severe β-cell loss and hyperglycemia. Understanding disease pathophysiology is critical for identifying biomarkers and therapeutic targets, and animal models play a key role in this process. In this study, we re-analyzed published transcriptomic and proteomi...

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Literature Corpus work: 5950f2d5-155a-5311-990e-623b7c350d33
DOI: 10.64898/2026.03.04.707880

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