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Chronic hyperglycaemia drives functional impairment of lymphocytes in diabetic <i>INS</i> <sup>C94Y</sup> transgenic pigs

2020-08-27

Abstract excerpt

People with diabetes mellitus have an increased risk for infections, however, there is still a critical gap in precise knowledge about altered immune mechanisms in this disease. Since diabetic INS C94Y transgenic pigs exhibit elevated blood glucose and a stable diabetic phenotype soon after birth, they provide a favourable model to explore functional alterations of immune cells in an early stage of diabetes melli...

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Literature Corpus work
de6db3b4-b935-5138-82d7-0cc9f29147eb
DOI
10.1101/2020.08.26.267914
Open publication

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Chronic hyperglycaemia drives functional impairment of lymphocytes in diabetic <i>INS</i> <sup>C94Y</sup> transgenic pigsDOI 10.1101/2020.08.26.267914
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