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Article

Yearning for machine learning: applications for the classification and characterisation of senescence.

Cell and tissue research - 1 Oct 2023

Hughes Bethany K, Wallis Ryan, Bishop Cleo L

Abstract excerpt

Senescence is a widely appreciated tumour suppressive mechanism, which acts as a barrier to cancer development by arresting cell cycle progression in response to harmful stimuli. However, senescent cell accumulation becomes deleterious in aging and contributes to a wide range of age-related pathologies. Furthermore, senescence has beneficial roles and is associated with a growing list of normal physiological...

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PMID: 37016180
DOI: 10.1007/s00441-023-03768-4
PMCID: PMC10558380

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