Article

A Prodrug Strategy to Reposition Atovaquone as a Long-Acting Injectable for Malaria Chemoprotection

2024-02-12

Abstract excerpt

<h4>ABSTRACT</h4> Recent malaria drug discovery approaches have been extensively focused on the development of oral, smallmolecule inhibitors for disease treatment whereas parenteral routes of administration have been avoided due to limitations in deploying a shelf-stable injectable even though it could be dosed less frequently. However, an updated target candidate profile from Medicines for Malaria Venture (MMV)...

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Literature Corpus work: 592235a7-d72a-539a-bd31-6e46e39c8870
DOI: 10.1101/2024.02.08.579395

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