Article

Atovaquone for Treatment of COVID-19: A Prospective Randomized, Double-Blind, Placebo-Controlled Clinical Trial

2022-05-25

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> An in-silico screen was performed to identify FDA approved drugs that inhibit SARS-CoV-2 main protease (M pro ), followed by in vitro viral replication assays, and in vivo pharmacokinetic studies in mice. These studies identified atovaquone as a promising candidate for inhibiting viral replication. <h4>Methods</h4> A 2-center, randomized, double-blind, placebo-controlled trial...

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Literature Corpus work: 3e541656-26ec-527f-86a2-74aaaf4a9d78
DOI: 10.1101/2022.05.24.22275411

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