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Asleep at the Wheel: Forward Genetic ENU Mutagenesis Screen for Mouse Models of Chronic Fatigue Identifies a Mutation in <i>Slc2a4</i> (GLUT4)

2017-07-13

Abstract excerpt

<h4>ABSTRACT</h4> In a screen of voluntary wheel-running behavior designed to identify genetic mouse models of chronic fatigue in ENU mutagenized C57BL/6J mice, we discovered two lines that showed aberrant wheel-running patterns. These lines both stem from a single original founder identified as a low body-weight candidate in a recessive screen. Progeny from both of these lines showed the abnormal wheel-running b...

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Literature Corpus work
5914d361-212b-5b0d-a8fc-021d81874d4c
DOI
10.1101/163378
Open publication

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Asleep at the Wheel: Forward Genetic ENU Mutagenesis Screen for Mouse Models of Chronic Fatigue Identifies a Mutation in <i>Slc2a4</i> (GLUT4)DOI 10.1101/163378
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