Article
Glycogen storage and muscle glucose transporters (GLUT-4) of mice selectively bred for high voluntary wheel running.
The Journal of experimental biology - 1 Jan 2009
Gomes Fernando R, Rezende Enrico L, Malisch Jessica L, Lee Sun K, Rivas Donato A, Kelly Scott A, Lytle Christian, Yaspelkis Ben B, Garland Theodore
Abstract excerpt
To examine the evolution of endurance-exercise behaviour, we have selectively bred four replicate lines of laboratory mice (Mus domesticus) for high voluntary wheel running (;high runner' or HR lines), while also maintaining four non-selected control (C) lines. By generation 16, HR mice ran approximately 2.7-fold more than C mice, mainly by running faster (especially in females), a differential maintained through...
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