Article

Integrative Pan-cancer Analysis of MEK1 Aberrations and the Potential Clinical Implications

2021-04-09

Abstract excerpt

<h4>Background: </h4> Alterations of mitogen-activated protein kinase kinase 1 (MEK1) are commonly associated with tumorigenesis, and MEK1 is thought to be a suitable targeted therapy for various cancers. However, abnormal MEK1 alterations and their relevant clinical implications are unknown. Our research comprehensively analyzed the MEK1 alteration spectrum and provided novel insight for targeted therapies. <h4>M...

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Literature Corpus work: 58bcd6d9-ddb2-50da-9450-8b54fdf7cdc5
DOI: 10.21203/rs.3.rs-392196/v1

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