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Analysis of Genetic Alterations in Cutaneous Malignant Melanomas Unveils Unique Loco-Regional Variations and Novel Predictors of Metastatic Potential.

The American Journal of dermatopathology - 1 Dec 2021

Krishnamurthy Kritika, Urioste Sophia N, Cusnir Mike, Schwartz Michael, Alghamdi Sarah, Sriganeshan Vathany, Poppiti Robert

Abstract excerpt

ABSTRACT: Cutaneous malignant melanoma is an aggressive cancer that contributes significantly to cancer-related mortality. Over the years, a deeper scrutiny of melanoma biology has led to identification of diverse evolutionary patterns involving various genetic pathways. This study attempts to further understand the genetic landscape of cutaneous malignant melanoma in terms of loco-regional variations and...

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Biomarkers, Tumor
Melanoma
Melanoma, Cutaneous Malignant
Mutation

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PMID: 33859081
DOI: 10.1097/DAD.0000000000001953

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