Article

Yorzoi: Predicting RNA-seq coverage from DNA sequence in yeast

2025-09-20

Abstract excerpt

Yeast is one of the principal model organisms in synthetic biology and a widely used chassis for testing heterologous DNA sequences. However, designing DNA constructs correctly is currently limited by our incomplete quantitative understanding of how sequences are transcribed and translated, especially non-native sequences. Here, we present Yorzoi , a sequence-to-expression model for bakers’ yeast that predicts RN...

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Literature Corpus work: 5899c38f-5503-514f-a1f7-362f7e5da011
DOI: 10.1101/2025.09.20.677345

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