Article

Phenotypic and Genomic Associations of a Common Executive Function Factor and the p-Factor with the Big Five Personality Traits

2025-07-07

Abstract excerpt

<title>Abstract</title> <p>A substantial number of patients with mental disorders struggle with goal-directed behavior. Both differences in personality and executive functions (EFs) are studied as potential mediators. On a latent level, EFs are highly heritable and have been shown to represent a genomic neurocognitive correlate of mental disorders. Here, we study the interplay of a latent common EF factor (cEF),...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5893219f-3523-5fe5-8ca7-e3acdeb797b8
DOI: 10.21203/rs.3.rs-6843541/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Phenotypic and Genomic Associations of a Common Executive Function Factor and the p-Factor with the Big Five Personality TraitsDOI 10.21203/rs.3.rs-6843541/v1Read

"The Heidelberg Five" personality dimensions: Genome-wide associations, polygenic risk for neuroticism, and psychopathology 20 years after assessment.Semantic proximity Read

“The Heidelberg Five” Personality Dimensions: Genome-wide Associations, Polygenic Risk for Neuroticism, and Psychopathology 20 Years after AssessmentSemantic proximity Read

Multivariate genetic analysis of personality and cognitive traits reveals abundant pleiotropy.Semantic proximity Read

A genome-wide investigation into the underlying genetic architecture of personality traits and overlap with psychopathologySemantic proximity Read

Heritability estimates of the Big Five personality traits based on common genetic variants.Semantic proximity Read

Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders.Semantic proximity Read

Polygenic scores for executive functioning as predictors of performance improvements after repeated testing in major psychiatric disorders.Semantic proximity Read

Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium.Semantic proximity Read

Pleiotropy of polygenic factors associated with focal and generalized epilepsy in the general populationSemantic proximity Read

The genetics of human personality.Semantic proximity Read

Identification of genetic loci shared between schizophrenia and the Big Five personality traits.Semantic proximity Read

Robust inference and widespread genetic correlates from a large-scale genetic association study of human personalitySemantic proximity Read