"The Heidelberg Five" personality dimensions: Genome-wide associations, polygenic risk for neuroticism, and psychopathology 20 years after assessment.

doi:10.1002/ajmg.b.32837

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Article

"The Heidelberg Five" personality dimensions: Genome-wide associations, polygenic risk for neuroticism, and psychopathology 20 years after assessment.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Mar 2021

Heilbronner Urs, Papiol Sergi, Budde Monika, Andlauer Till F M, Strohmaier Jana, Streit Fabian, Frank Josef, Degenhardt Franziska, Heilmann-Heimbach Stefanie, Witt Stephanie H, Forstner Andreas J, Loerbroks Adrian, Amelang Manfred, Stürmer Til, Müller-Myhsok Bertram, Nöthen Markus M, Rietschel Marcella, Schulze Thomas G

Abstract excerpt

HeiDE is a longitudinal population-based study that started in the 1990s and, at baseline, assessed an array of health-related personality questionnaires in 5133 individuals. Five latent personality dimensions (The Heidelberg Five) were identified and interpreted as Emotional Lability (ELAB), Lack of Behavioral Control (LBCN), Type A Behavior (TYAB), Locus of Control over Disease (LOCC), and Psychoticism (PSYC)....

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PMID: 33590662
DOI: 10.1002/ajmg.b.32837

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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