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Antibody escape and cryptic cross-domain stabilization in the SARS-CoV-2 Omicron spike protein

2022-04-18

Abstract excerpt

<h4>Summary</h4> The worldwide spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to the repeated emergence of variants of concern. The Omicron variant has two dominant sub-lineages, BA.1 and BA.2, each with unprecedented numbers of nonsynonymous and indel spike protein mutations: 33 and 29, respectively. Some of these mutations individually increase transmissibility and enhance immune...

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Literature Corpus work
58743f5d-06b2-5fbc-94b4-37a474c14c29
DOI
10.1101/2022.04.18.488614
Open publication

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Antibody escape and cryptic cross-domain stabilization in the SARS-CoV-2 Omicron spike proteinDOI 10.1101/2022.04.18.488614
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