Article

Cohort-specific Boolean models highlight different regulatory modules during Parkinson’s disease progression

2024-02-22

Abstract excerpt

1 Parkinson’s Disease (PD) is a multifaceted neurodegenerative disorder characterised by complex molecular dysregulations and diverse comorbidities. It is critical to decode the molecular pathophysiology of PD, which involves complex molecular interactions and their changes over time. Systems medicine approaches can help with this by a) encoding knowledge about the mechanisms into computational models b) simulatin...

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Literature Corpus work: 586a14ed-35ee-51ab-938d-69aa1a1e61a4
DOI: 10.1101/2024.02.20.581152

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