Article

Disambiguate: An open-source application for disambiguating two species in next generation sequencing data from grafted samples

2017-01-24

Abstract excerpt

Grafting of cell lines and primary tumours is a crucial step in the drug development process between cell line studies and clinical trials. Disambiguate is a program for computationally separating the sequencing reads of two species derived from grafted samples. Disambiguate operates on DNA or RNA-seq alignments to the two species and separates the components at very high sensitivity and specificity as illustrat...

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Literature Corpus work: 5855f9be-cba9-5ea7-802c-990256b774ea
DOI: 10.12688/f1000research.10082.2

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