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Establishment and characterisation of patient-derived xenografts as paraclinical models for gastric cancer

1 Mar 2016

Abstract excerpt

The patient-derived xenograft (PDX) model is emerging as a promising translational platform to duplicate the characteristics of tumours. However, few studies have reported detailed histological and genomic analyses for model fidelity and for factors affecting successful model establishment of gastric cancer. Here, we generated PDX tumours surgically-derived from 62 gastric cancer patients. Fifteen PDX models were...

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Cancer Cells and Metastasis
Cancer Genomics and Diagnostics
Cancer Research and Treatments

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26926953
DOI: 10.1038/srep22172

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