Article

Evolutionary and cellular analysis of the dark pseudokinase PSKH2

2022-09-10

Abstract excerpt

Pseudokinases, so named because they lack one or more conserved canonical amino acids that define their catalytically-active relatives, have evolved a variety of biological functions in both prokaryotic and eukaryotic organisms. Human PSKH2 is closely related to the canonical kinase PSKH1, which maps to the CAMK family of protein kinases. Primates encode PSKH2 in the form of a pseudokinase, which is predicted to b...

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Literature Corpus work: 582c155d-26e8-5fef-a917-8793f060576f
DOI: 10.1101/2022.09.10.507278

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