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Identification of potent human neutralizing antibodies against SARS-CoV-2 implications for development of therapeutics and prophylactics

9 Aug 2021

Abstract excerpt

Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus that is spreading rapidly, which seriously impacts global public health and economy. Thus, developing effective drugs remains urgent. We identify two potent antibodies, nCoVmab1 and nCoVmab2, targeting the SARS-CoV-2 spike protein receptor-binding domain (RBD) with high affinities from a naïve human phage-displayed Fab...

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PMID: 34373446
DOI: 10.1038/s41467-021-25153-x

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