Article

Maternal sterol 27-hydroxylase is crucial for securing fetal development

2023-11-12

Abstract excerpt

<h4>Summary</h4> The maternal body helps in providing nutrients and degrading toxic metabolites instead of the fetal body; disruptions in these mechanisms affect normal fetal development. Sterol 27-hydroxylase ( Cyp27a1 ) is involved in the alternative pathway of bile acid synthesis, which is enhanced during pregnancy. However, its role in fetal development remains unclear. Here, we demonstrate that maternal Cyp...

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Literature Corpus work: 57b834be-392c-54dd-ab08-8b87ed3bed2e
DOI: 10.1101/2023.11.08.566330

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