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Article

Analysis of CYP27A1 mutations in Han Chinese women with intrahepatic cholestasis of pregnancy.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians - 1 Dec 2022

Xin Siming, Liu Xianxian, Liu Huai, Zeng Xiaoming, Xiong Ying, Zhou Mengni, Zou Yang, Zeng Yang, Zheng Jiusheng, Lai Hua

Abstract excerpt

OBJECTIVE: To explore the cytochrome P450 family 27 subfamily A member 1 (CYP27A1) gene mutations in Chinese women with intrahepatic cholestasis of pregnancy (ICP) and the correlation between CYP27A gene mutations and BA (bile acid) level changes. METHODS: In this study, the entire coding region of the CYP27A1 gene was sequenced in 151 Han Chinese women with ICP and 1029 matched samples, and the pathogenicity of...

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Identifiers

PMID: 34930075
DOI: 10.1080/14767058.2021.2020239

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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