Article
USMPep: universal sequence models for major histocompatibility complex binding affinity prediction.
BMC bioinformatics - 2 Jul 2020
Vielhaben Johanna, Wenzel Markus, Samek Wojciech, Strodthoff Nils
Abstract excerpt
BACKGROUND: Immunotherapy is a promising route towards personalized cancer treatment. A key algorithmic challenge in this process is to decide if a given peptide (neoepitope) binds with the major histocompatibility complex (MHC). This is an active area of research and there are many MHC binding prediction algorithms that can predict the MHC binding affinity for a given peptide to a high degree of accuracy....
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