Article

A Bayesian Precision Medicine Framework for Calibrating Individualized Therapeutic Indices in Cancer

2021-08-10

Abstract excerpt

The development and clinical implementation of evidence-based precision medicine strategies has become a realistic possibility, primarily due to the rapid accumulation of large-scale genomics and pharmacological data from diverse model systems: patients, cell-lines and drug perturbation studies. We introduce a novel Bayesian modeling framework called the i ndividualized the R apeutic inde x (iR x ) model to in...

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Literature Corpus work: 7a593f75-5a69-5922-b045-d0cc47ae03e2
DOI: 10.1101/2021.08.09.455722

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