Article

MERFISH+, a large-scale, multi-omics spatial technology resolves the molecular holograms of the 3D human developing heart

2025-11-04

Abstract excerpt

<h4>Summary</h4> Hybridization-based spatial transcriptomics technologies have advanced our ability to map cellular and subcellular organization in complex tissues. However, existing methods remain constrained in gene coverage, multimodal compatibility, and scalability. Here, we present MERFISH+, an enhanced version of Multiplexed Error-Robust Fluorescence in Situ Hybridization (MERFISH), which integrates chemica...

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Literature Corpus work: a00f1141-8c0a-5a41-bc74-36b73fa9c421
DOI: 10.1101/2025.11.02.686137

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