Article

Systemic Analysis of the Dna Replication Regulators Origin Recognition Complex in Lung Adenocarcinomas Identifies Prognostic and Expression Significance

2021-07-08

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Origin recognition complex (ORC) 1, ORC2, ORC3, ORC4, ORC5 and ORC6, form a replication-initiator complex to mediate DNA replication, which play a key role in carcinogenesis, while their role in lung adenocarcinomas (LUAD) remains poorly understood.<bold>Methods: </bold>We confirmed the transcriptional and post-transcriptional levels, DNA alteration, DNA methyla...

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Literature Corpus work: 0a6b5462-3fd4-5097-96b9-875405a5fcf3
DOI: 10.21203/rs.3.rs-487176/v2

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