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Article

Host adaptation drives genetic diversity in a vector-borne disease system

1 Aug 2023

Abstract excerpt

Abstract The range of hosts a pathogen can infect is a key trait, influencing human disease risk and reservoir host infection dynamics. Borrelia burgdorferi sensu stricto (Bb), an emerging zoonotic pathogen, causes Lyme disease and is widely considered a host generalist, commonly infecting mammals and birds. Yet the extent of intraspecific variation in Bb host breadth, its role in determining host competence, and...

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PMID: 37559749
DOI: 10.1093/pnasnexus/pgad234

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