Article
TEDEdb: a large-scale resource and multi-cohort analysis of transposable element differential expression in cancer
2026-04-29
Abstract excerpt
The human genome consists of nearly 50% repetitive DNA, referred to for decades as “junk DNA”. These repetitive sequences, usually under the strict control of epigenetic silencing, have been observed to be aberrantly expressed in cancer. Some of these expressed sequences, e.g., transposable elements (TEs), can induce innate immune responses when de-repressed following treatment with epigenetic therapies. As a resu...
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Identifiers and source
- Literature Corpus work
- 574af2a0-86a2-5b09-b346-3f738d22ca28
- DOI
- 10.64898/2026.04.27.721042