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Pan-cancer RNA editing activity reveals complex editing functions and cancer immunotherapy biomarkers

2026-01-08

Abstract excerpt

Pervasive RNA editing in human diversifies the transcriptome and proteome. However, biological functions of most RNA editing sites remain to be uncovered. Here, we developed a computational framework (iPEAPR) to investigate editing functions in various pathways and regulatory elements, by using only summary information of millions of editing sites, in >5,000 cancer samples and in >2,500 normal samples, and large n...

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Literature Corpus work
5a32b257-24b6-56e6-b4da-3bb49a5af59b
DOI
10.64898/2026.01.07.698309
Open publication

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Pan-cancer RNA editing activity reveals complex editing functions and cancer immunotherapy biomarkersDOI 10.64898/2026.01.07.698309
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