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Hallmarks of Cancer: The Next Generation

1 Mar 2011

Abstract excerpt

The hallmarks of cancer comprise six biological capabilities acquired during the multistep development of human tumors. The hallmarks constitute an organizing principle for rationalizing the complexities of neoplastic disease. They include sustaining proliferative signaling, evading growth suppressors, resisting cell death, enabling replicative immortality, inducing angiogenesis, and activating invasion and...

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Identifiers

PMID: 21376230
DOI: 10.1016/j.cell.2011.02.013

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