Article
Genetic variants of lncRNA HOTAIR and risk of epithelial ovarian cancer among Chinese women.
Oncotarget - 5 Jul 2016
Wu Haijing, Shang Xiaofei, Shi Yu, Yang Zhirong, Zhao Jun, Yang Min, Li Yan, Xu Shiqiang
Abstract excerpt
Ovarian cancer is one of the common female malignant tumors globally. However, exactly mechanism of ovarian cancer remained unknown. HOTAIR, a lncRNA in the mammalian HOXC locus, has been fully explored for its genetic variants, expression level and carcinogenesis, development and progression of multiple cancers, except for ovarian cancer. In this study, we hypothesized that abnormal expression of HOTAIR and...
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