Impact of HLA Class I Antigen, Killer Ig-like Receptor and FCGR3A Genotypes in Breast Cancer Susceptibility and Tumor stage

Abstract excerpt

<title>Abstract</title> <p>The identification of clinical pathological role of genes regulating NK cell function, including HLA, KIR and FCGR3A, in breast cancer (BC) may be a challenge. The objective of this study was to determine whether these genes have an impact on the BC susceptibility and progression. In this study, 47 BC Italian patientswere genotyped by PCR-SSP typing (KIR) and PCR-SBT method (HLA-C and F...

Topics

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• Alleles
• Breast Neoplasms
• Case-Control Studies
• Histocompatibility Antigens Class I
• HLA-C Antigens
• Neoplasm Staging
• Receptors, IgG
• Receptors, KIR

Identifiers and source

Literature Corpus work

56d21f5a-9b19-5ac8-ad8d-88a9325a5af0

DOI

10.21203/rs.3.rs-1860861/v1