Article
Determination of genetic predisposition to early breast cancer in women of Kazakh ethnicity.
Oncotarget - 4 Oct 2023
Zhunussova Gulnur, Omarbayeva Nazgul, Kaidarova Dilyara, Abdikerim Saltanat, Mit Natalya, Kisselev Ilya, Yergali Kanagat, Zhunussova Aigul, Goncharova Tatyana, Abdrakhmanova Aliya, Djansugurova Leyla
Abstract excerpt
Breast cancer (BC) is the most common type of cancer among women in Kazakhstan. To date, little data are available on the spectrum of genetic variation in Kazakh women with BC. We aimed to identify population-specific genetic markers associated with the risk of developing early-onset BC and test their association with clinical and prognostic factors. The study included 224 Kazakh women diagnosed with BC (≤40...
Topics
- Humans
- Female
- Genetic Predisposition to Disease
- Ethnicity
- Triple Negative Breast Neoplasms
- Dermatitis
- Exons