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Perturbation of the insomnia <i>WDR90</i> GWAS locus pinpoints rs3752495 as a causal variant influencing distal expression of neighboring gene, <i>PIG-Q</i>

2023-08-18

Abstract excerpt

<h4>ABSTRACT</h4> Although genome wide association studies (GWAS) have been crucial for the identification of loci associated with sleep traits and disorders, the method itself does not directly uncover the underlying causal variants and corresponding effector genes. The overwhelming majority of such variants reside in non-coding regions and are therefore presumed to impact the activity of cis -regulatory elemen...

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Literature Corpus work
56a475da-58ff-5cc9-97fa-343f9b23eaf9
DOI
10.1101/2023.08.17.553739
Open publication

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Perturbation of the insomnia <i>WDR90</i> GWAS locus pinpoints rs3752495 as a causal variant influencing distal expression of neighboring gene, <i>PIG-Q</i>DOI 10.1101/2023.08.17.553739
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