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Article

[Study of hypermethylation of SOCS gene in typical myeloproliferative disease].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Nov 2011

Qin Wei, Li Ling-li, Lu Hui-na, Huang Bin-bin, Xiu Bing, Bo Lan-jun, Gao Qing-mei, Zhang Wen-jun, Fu Jian-fei

Abstract excerpt

OBJECTIVE: To investigate the clinical role of hypermethylation of suppressor of cytokine signaling (SOCS) on typical myeloproliferative disease (MPD) patients and its mechanism. METHODS: Methylation specific PCR was used to detect SOCS1, 2, 3 methylation, direct DNA sequencing was performed to detect JAK2V617F mutation, real-time fluorescence quantitative PCR were applied to evaluate transcriptional activity of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22339915

Genes

SOCS1
SOCS2
SOCS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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