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Article

Association between methylation of tumor suppressor gene SOCS1 and acute myeloid leukemia

19 Jun 2018

Abstract excerpt

Suppressor of cytokine signaling‑1 (SOCS1) is a widely recognized tumor suppressor gene. Silencing of SOCS1 expression as a result of promoter methylation is associated with occurrence and development of solid tumors such as liver, cervical and pancreatic cancer. However, the association between SOCS1 gene methylation and acute myeloid leukemia (AML) has not been well explored. In the present study, we examined...

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PMID: 29916533
DOI: 10.3892/or.2018.6508

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