Article

Is Tau the Initial Pathology in Dopaminergic Nigrostriatal Degeneration? Studies in Parkinsonism and Parkinson’s Disease

2022-08-06

Abstract excerpt

While Parkinson’s disease (PD) remains clinically defined by cardinal motor symptoms resulting from nigrostriatal degeneration, it is now appreciated that PD consists of multiple pathologies, but it is unclear which occurs first and which are responsible for the nigrostriatal degeneration. For the past number of years, we have been studying a well-characterized cohort of subjects with motor impairment that we have...

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Literature Corpus work: 5638dc41-d87a-566c-b79e-8d95debeb411
DOI: 10.1101/2022.08.04.502831

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