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Article

Early diagnosis of Parkinson's disease.

Journal of neurology - 1 Oct 2002

Becker Georg, Müller Antje, Braune Stefan, Büttner Thomas, Benecke Reiner, Greulich Wolfgang, Klein Wolfgang, Mark Günter, Rieke Jürgen, Thümler Reiner

Abstract excerpt

In idiopathic Parkinson's disease (IPD) approximately 60 % of the nigrostriatal neurons of the substantia nigra (SN) are degenerated before neurologists can establish the diagnosis according to the widely accepted clinical diagnostic criteria. It is conceivable that neuroprotective therapy starting at such an 'advanced stage' of the disease will fail to stop the degenerative process. Therefore, the identification...

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Identifiers

PMID: 12522572
DOI: 10.1007/s00415-002-1309-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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