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Positive selection and gene duplications in tumour suppressor genes reveal clues about how cetaceans resist cancer

2020-01-16

Abstract excerpt

Cetaceans are the longest-living species of mammals and the largest in the history of the planet. They have developed mechanisms against diseases such cancer, although the underlying molecular bases of these remain unknown. The goal of this study was to investigate the role of natural selection in the evolution of 1077 tumour suppressor genes (TSGs) in cetaceans. We used a comparative genomic approach to analyse t...

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Literature Corpus work
56267c0f-e662-5a93-ba1c-431d376ec471
DOI
10.1101/2020.01.15.908244
Open publication

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Positive selection and gene duplications in tumour suppressor genes reveal clues about how cetaceans resist cancerDOI 10.1101/2020.01.15.908244
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