Article
The molecular evolution of cancer associated genes in mammals.
Scientific reports - 22 May 2024
MacDonald Nick, Raven Nynke, Diep Wendy, Evans Samantha, Pannipitiya Senuri, Bramwell Georgina, Vanbeek Caitlin, Thomas Frédéric, Russell Tracey, Dujon Antoine M, Telonis-Scott Marina, Ujvari Beata
Abstract excerpt
Cancer is a disease that many multicellular organisms have faced for millions of years, and species have evolved various tumour suppression mechanisms to control oncogenesis. Although cancer occurs across the tree of life, cancer related mortality risks vary across mammalian orders, with Carnivorans particularly affected. Evolutionary theory predicts different selection pressures on genes associated with cancer...
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