Article

Cross-species identification of cancer-resistance associated genes uncovers their relevance to human cancer risk

2021-05-21

Abstract excerpt

<h4>ABSTRACT</h4> Cancer is an evolutionarily conserved disease that occurs in a wide variety of species. We applied a comparative genomics approach to systematically characterize the genes whose conservation levels significantly correlates positively (PC) or negatively (NC) with a broad spectrum of cancer-resistance estimates, computed across almost 200 vertebrate species. PC genes are enriched in pathways relev...

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Literature Corpus work: cede2fbe-c9eb-59c6-ae0a-0fff4cc09bc6
DOI: 10.1101/2021.05.19.444895

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