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Article

The RNA-binding landscape of RBM10 and its role in alternative splicing regulation in models of mouse early development.

RNA biology - 2 Jan 2017

Rodor Julie, FitzPatrick David R, Eyras Eduardo, Cáceres Javier F

Abstract excerpt

Mutations in the RNA-binding protein, RBM10, result in a human syndromic form of cleft palate, termed TARP syndrome. A role for RBM10 in alternative splicing regulation has been previously demonstrated in human cell lines. To uncover the cellular functions of RBM10 in a cell line that is relevant to the phenotype observed in TARP syndrome, we used iCLIP to identify its endogenous RNA targets in a mouse embryonic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 27763814
DOI: 10.1080/15476286.2016.1247148
PMCID: PMC5270529

Genes

RBM10
TARP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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