Article
Half pint regulates alternative splice site selection in Drosophila.
Developmental cell - 1 Mar 2002
Van Buskirk Cheryl, Schüpbach Trudi
Abstract excerpt
Alternative splicing is used by metazoans to increase protein diversity and to alter gene expression during development. However, few factors that control splice site choice in vivo have been identified. Here we describe a factor, Half pint (Hfp), that regulates RNA splicing in Drosophila. Females harboring hypomorphic mutations in hfp lay short eggs and show defects in germline mitosis, nuclear morphology, and...
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