Article

Parabrachial CGRP Neurons Regulate Opioid Reinforcement

2026-03-20

Abstract excerpt

Opioid use disorder (OUD) is a chronic, relapsing disease driven by the reinforcing properties of opioids and perpetuated by avoidance of the negative affective states associated with the absence of the drug. Most available OUD treatments directly engage the µ-opioid receptor and may induce side effects that can compromise their therapeutic efficacy, thus underscoring the need for novel therapeutic alternatives. C...

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Literature Corpus work: 485717c5-a40f-5318-b8c1-abd2991c5126
DOI: 10.64898/2026.03.18.712659

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