Article

Disruption of androgen receptor-cofactor interactions by the RNA-binding protein FUS/TLS alters androgen signalling in prostate cancer

2025-05-22

Abstract excerpt

<title>Abstract</title> <p>Prostate cancer is dependent upon the androgen receptor, the activity of which is modified by cofactors that either enhance or repress its activity, often in a context-dependent manner. FUS/TLS is a multifunctional protein known to be important in multiple cancer types; in prostate cancer, we previously showed that FUS has a potential tumour suppressor role. Here, transcriptomic analysi...

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Literature Corpus work: 55e57d56-ed6a-5937-88d1-ff457230cb67
DOI: 10.21203/rs.3.rs-6609773/v1

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