Article
Transcriptome Sequencing Reveals PCAT5 as a Novel ERG-Regulated Long Noncoding RNA in Prostate Cancer.
Cancer research - 1 Oct 2015
Ylipää Antti, Kivinummi Kati, Kohvakka Annika, Annala Matti, Latonen Leena, Scaravilli Mauro, Kartasalo Kimmo, Leppänen Simo-Pekka, Karakurt Serdar, Seppälä Janne, Yli-Harja Olli, Tammela Teuvo L J, Zhang Wei, Visakorpi Tapio, Nykter Matti
Abstract excerpt
Castration-resistant prostate cancers (CRPC) that arise after the failure of androgen-blocking therapies cause most of the deaths from prostate cancer, intensifying the need to fully understand CRPC pathophysiology. In this study, we characterized the transcriptomic differences between untreated prostate cancer and locally recurrent CRPC. Here, we report the identification of 145 previously unannotated intergenic...
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