Back to search

Article

A multimodal cross-species comparison of pancreas development

2024-04-04

Abstract excerpt

<title>Abstract</title> <p>Human pancreas development remains incompletely understood due to limited sample access constrained by ethical and practical considerations. Here we investigate whether pigs resemble humans in pancreas development more closely than rodents, and as such, offer a valuable alternative large-animal model. As pig pancreas organogenesis is unexplored, we first annotated developmental hallmark...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
98e4521e-8bca-541d-8243-e350deb92ad9
DOI
10.21203/rs.3.rs-4151759/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
A multimodal cross-species comparison of pancreas developmentDOI 10.21203/rs.3.rs-4151759/v1
Molecular and genetic regulation of pig pancreatic islet cell developmentSemantic proximity
Molecular and genetic regulation of pig pancreatic islet cell developmentSemantic proximity
Deciphering early human pancreas development at the single-cell levelSemantic proximity
A postnatal network of co-hepato/pancreatic stem/progenitors in the biliary trees of pigs versus humansSemantic proximity
Mapping histologic and functional maturation of human endocrine pancreas across early postnatal periodsSemantic proximity
Transcription factors that shape the mammalian pancreasSemantic proximity
A postnatal network of co-hepato/pancreatic stem/progenitors in the biliary trees of pigs and humansSemantic proximity
Single cell transcriptomic and spatial landscapes of the developing human pancreasSemantic proximity
Understanding human fetal pancreas development using subpopulation sorting, RNA sequencing and single-cell profilingSemantic proximity
A transcriptional cross species map of pancreatic islet cellsSemantic proximity
Endocrine islet β-cell subtypes with differential function are derived from biochemically distinct embryonic endocrine islet progenitors that are regulated by maternal nutrientsSemantic proximity
Gene expression analysis of mammary tissue during fetal bud formation and growth in two pig breeds--indications of prenatal initiation of postnatal phenotypic differences.Semantic proximity
Select a neighboring publication to make it the new centre.