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Endocrine Cell Clustering During Human Pancreas Development

13 Apr 2009

Abstract excerpt

The development of efficient, reproducible protocols for directed in vitro differentiation of human embryonic stem (hES) cells into insulin-producing beta cells will benefit greatly from increased knowledge regarding the spatiotemporal expression profile of key instructive factors involved in human endocrine cell generation. Human fetal pancreases 7 to 21 weeks of gestational age, were collected following consent...

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Identifiers

PMID: 19365093
DOI: 10.1369/jhc.2009.953307

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