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Insulin is expressed by enteroendocrine cells during human fetal development

2021-06-07

Abstract excerpt

Generation of beta cells via transdifferentiation of other cell types is a promising avenue for the treatment of diabetes. Here, we reconstruct a single cell atlas of enteroendocrine cells in the human fetal and neonatal small intestine. We identify a subset of fetal enteroendocrine K/L cells that express high levels of insulin and other beta cell genes. Our findings highlight a potential extra-pancreatic source o...

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Literature Corpus work
0526381d-525e-5e48-bdaf-5d891cd2e726
DOI
10.1101/2021.06.07.447234
Open publication

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Insulin is expressed by enteroendocrine cells during human fetal developmentDOI 10.1101/2021.06.07.447234
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